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MMP |
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Both macrophage dysfunction and increased activity of matrix metalloproteinase (MMP) have been reported. British Biotech, Oxford, England, has reported the results of Study 131, a Phase III clinical trial of the oral matrix metalloproteinase inhibitor, marimastat. Matrix metalloproteinase activity is required for the inflammatory cell infiltration that occurs following spinal cord injury and most likely contributes to early barrier disruption. |
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