MDM2

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Acronym	Definition
MDM2	Mouse Double Minute 2

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In the absence of functional p53 protein, cells lose genomic integrity and are prone to cancer development, p53 functions as a transcription factor up-regulating many target genes, such as p21 (cydin-dependent kinase inhibitor 1A, Cipl), MDM2 (transformed 3T3 cell double minute 2), and GADD45 (growth arrest and DNA-damage-inducible, alpha) (Levine 1997). Distinct gene expression profiles in immortalized human urothelial ... by Te-Chang, Lee / Environmental Health Perspectives DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Phosphorylation of p53 protein in A549 human pulmonary epithelial ... by Morimoto, Yasuo / Environmental Health Perspectives More results

? References in periodicals archive

In the absence of functional p53 protein, cells lose genomic integrity and are prone to cancer development, p53 functions as a transcription factor up-regulating many target genes, such as p21 (cydin-dependent kinase inhibitor 1A, Cipl), MDM2 (transformed 3T3 cell double minute 2), and GADD45 (growth arrest and DNA-damage-inducible, alpha) (Levine 1997).

Distinct gene expression profiles in immortalized human urothelial ... by Te-Chang, Lee / Environmental Health Perspectives

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2.

Phosphorylation of p53 protein in A549 human pulmonary epithelial ... by Morimoto, Yasuo / Environmental Health Perspectives

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MDLT
MDLTP
MDLU
MDLUG
MDLVQ
MDM
MDM-2
MDM2
MDMA
MDMB
MDMC
MDMD
MDMDFSS
MDME
MDMEI

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