Evidence from an autopsy study of adults has suggested strong correlations between levels of total Hg in toenails and MeHg
levels in blood or occipital cortex (Bjorkman et al.
This effect should be incorporated into policy and management efforts aimed at reducing human health risks from MeHg
exposure," they added.
Existing Health Canada blood MeHg
guidance values were recently expanded to include a harmonized provisional guidance value for children, pregnant women and women of childbearing age (16-49 years).
exposure occurs mainly through the consumption of mercury-contaminated fish.
genes that can convert MeHg
back to its volatile form; for example,
2-4) The studies about MeHg
toxicity became ubiquitous and diversified since the outbreak of environmental catastrophes such as those in Minamata (1950s) and Niigata (1960s).
Based on recent research of the effects of MeHg
on humans, recommendations for fish intake have been established for specific populations, including women of childbearing age, pregnant and lactating women, infants, and children in relation to central nervous system development (FDA 2004).
Abbreviations: Bt, Bryothamnion triquetrum; DHR 123, dihydrorhodamine 123; DMEM, Dulbecco's modified Eagle's medium; DPPH, 1, 1-diphenyl-2-picrylhydrazyl radical; FBS, foetal bovine serum; MeHg
, methyl mercury; NOS, nitric oxide synthase.
In the actual study, Burbacher states: "There was a much higher proportion of inorganic Hg [mercury] in the brain of Thimerosal infants than MeHg
infants (up to 71% vs.
not only has the ability to cross the blood-brain barrier, but its exceptionally high affinity for Se may enable it to specifically sequester Se and diminish selenoprotein synthesis.
is by far the most toxic form of mercury and the form that accumulates in food chains.
The report actually states that "over 60,000 newborns annually might be at risk for adverse neurodevelopmental effects from in utero exposure to MeHg