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Evidence from an autopsy study of adults has suggested strong correlations between levels of total Hg in toenails and MeHg levels in blood or occipital cortex (Bjorkman et al.
This effect should be incorporated into policy and management efforts aimed at reducing human health risks from MeHg exposure," they added.
Existing Health Canada blood MeHg guidance values were recently expanded to include a harmonized provisional guidance value for children, pregnant women and women of childbearing age (16-49 years).
MeHg exposure occurs mainly through the consumption of mercury-contaminated fish.
genes that can convert MeHg back to its volatile form; for example,
2-4) The studies about MeHg toxicity became ubiquitous and diversified since the outbreak of environmental catastrophes such as those in Minamata (1950s) and Niigata (1960s).
Based on recent research of the effects of MeHg on humans, recommendations for fish intake have been established for specific populations, including women of childbearing age, pregnant and lactating women, infants, and children in relation to central nervous system development (FDA 2004).
Abbreviations: Bt, Bryothamnion triquetrum; DHR 123, dihydrorhodamine 123; DMEM, Dulbecco's modified Eagle's medium; DPPH, 1, 1-diphenyl-2-picrylhydrazyl radical; FBS, foetal bovine serum; MeHg, methyl mercury; NOS, nitric oxide synthase.
MeHg not only has the ability to cross the blood-brain barrier, but its exceptionally high affinity for Se may enable it to specifically sequester Se and diminish selenoprotein synthesis.
The report actually states that "over 60,000 newborns annually might be at risk for adverse neurodevelopmental effects from in utero exposure to MeHg (methyl mercury).