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The researchers say that this supports their theory that learned emotional responses centered in the medial prefrontal cortex play a key role in the experience of chronic, or neuropathic, pain. 5) Previous studies of addictive behavior implicate abnormal functioning in a network of brain regions involved in reward-based decision-making (RBDM) that include the orbital and medial prefrontal cortex. Ironically, older individuals' reliance on the medial prefrontal cortex to regulate emotions comes as aging kills cells in this area. |
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