| Acronym | Definition |
|---|
| MEF | Marine Expeditionary Force |
| MEF | Ministerio de Economía y Finanzas (Spanish) |
| MEF | Metro Ethernet Forum |
| MEF | Managed Extensibility Framework (Microsoft .NET) |
| MEF | Mobile Entertainment Forum |
| MeF | Modernized E-File (IRS) |
| MEF | Middle East Forum (think tank) |
| MEF | Major Economies Forum |
| MEF | Mouse Embryonic Fibroblast |
| MEF | Modified Energy Factor |
| MEF | Malaysian Employers Federation |
| MEF | Malaita Eagle Force |
| MEF | Museo Paleontológico Egidio Feruglio (Patagonia, Argentina) |
| MEF | Middle East Force |
| MEF | Maximum Expiratory Flow |
| MEF | Metal-Enhanced Fluorescence |
| MEF | Mission Essential Function |
| MEF | MADS Box Transcription Enhancer Factor |
| MEF | Master Earnings File |
| MEF | Mindolo Ecumenical Foundation (Zambia) |
| MEF | Meksika Esperanto-Federacio (Mexican National Convention of Esperanto) |
| MEF | Mask Error Factor |
| MEF | Maximum Elevation Figures (aeronautics) |
| MEF | Maximum Expansion Factor (bullets) |
| MEF | Mission Execution Forecast (Air Force Weather Briefings) |
| MEF | Minimum Essential Force |
| MEF | Minimum Essential Facility |
| MEF | Major Equipment File |
| MEF | Mères et Femmes (French: Mothers Are Women; Ottawa, Ontario, Canada) |
| MEF | Ministry Expansion Fund |
| MEF | Mission Essential Force |
| MEF | Martingale Estimating Functions |
| MEF | Mobility Enhancement Fund |
| MEF | Materials Exposure Facility |
| MEF | Magnetics Environmental Filter |
| MEF | Montville Education Foundation |
| MEF | Minimum Elevation Figure (aeronautical maps) |
| MEF | Mature Equivalent of Fat |
| MEF | Mission Equipment Facility |
| MEF | Mouse Embryo Feeder (cells) |
| MEF | Mission Endowment Fund (various organizations) |