| Acronym | Definition |
|---|
| MCS | Multiple Chemical Sensitivity |
| MCS | Media Convergence Server (Cisco) |
| MCS | Memphis City Schools (Tennessee) |
| MCS | Motion City Soundtrack (band) |
| MCS | Marine Conservation Society |
| MCS | Multiple Cloning Site |
| MCS | Monitoring, Control and Surveillance |
| MCS | Microsoft Consulting Services |
| MCS | Mesoscale Convective System (meteorology) |
| MCS | Monte Carlo Simulation |
| MCS | Management Consulting Services |
| MCS | Modulation and Coding Scheme (HSDPA) |
| MCS | Maneuver Control System |
| MCS | Master Control Station |
| MCS | Mellon College of Science |
| MCS | Mars Climate Sounder (US NASA) |
| MCS | Master of Computer Science (degree) |
| MCS | Mechanical Circulatory Support |
| MCS | Millennium Cohort Study |
| MCS | Mellon College of Science (Carnegie Mellon university) |
| MCS | Multimedia Communications Server (Nortel) |
| MCS | Management Control System |
| MCS | Motion Control Systems |
| MCS | Mission Control System |
| MCS | Mounted Combat System |
| MCS | Modular Cooling System |
| MCS | Managed Care Support (TRICARE) |
| MCS | Material Control System |
| MCS | Monte Carlo Sampling |
| MCS | Mission Control Station |
| MCS | Mercalli-Cancani-Sieberg (geophysics scale) |
| MCS | Machinery Control System |
| MCS | Master Control System |
| MCS | Mobility Capabilities Study (DoD) |
| MCS | Manufacturing Control System |
| MCS | Mathematics in Computer Science (journal) |
| MCS | Multi-Channel Sound |
| MCS | Maryknoll Convent School |
| MCS | modular causeway system (US DoD) |
| MCS | Multi-Cloning Site |
| MCS | Middle Child Syndrome |
| MCS | Membership Capital Shares |
| MCS | Mountaineering Council of Scotland (Perth, Scotland) |
| MCS | Multiple Console Support (Telcordia) |
| MCS | Mass Communication Specialist (certification) |
| MCS | Message Conversion System |
| MCS | Maintenance Control System |
| MCS | Micro Current Stimulation (treatment of macular degeneration) |
| MCS | Minimal Cut Set |
| MCS | Mobile Camouflage System |
| MCS | Multipoint Communications System (Canada) |
| MCS | Monitor and Control System (Alcatel) |
| MCS | Meta Class System |
| MCS | Management Computer System |
| MCS | Miscellaneous Control Subsystem (Juniper Networks, Inc. routers) |
| MCS | Marine Corps Schools |
| MCS | Missile Control System |
| MCS | Microscopy, Culture and Sensitivity |
| MCS | Master of Commercial Science |
| MCS | Mobile Christian School (Alabama) |
| MCS | Multipoint Command Symmetrical Data-Transmission |
| MCS | Military Capabilities Study (US DoD) |
| MCS | Miles-Carpenter X-Linked Mental Retardation Syndrome |
| MCS | Master Control Switch |
| MCS | Maintenance Control Section (Royal Australian Air Force) |
| MCS | Multimedia Conference Servers (SWB) |
| MCS | Maintenance Control Subsystem |
| MCS | Multivendor Customer Service |
| MCS | Main-Channel Slope |
| MCS | Motherwell Control Systems (UK) |
| MCS | Management Conformance Summary (Telcordia) |
| MCS | Missile Control Subsystem |
| MCS | Multichannel Spectrometer |
| MCS | Milestone Car Society (Indianapolis, IN) |
| MCS | Multi-Cast Server |
| MCS | Maintenance Control Supervisor |
| MCS | Media Conversion Subsystem |
| MCS | Maritime Communications Subsystem |
| MCS | Multipoint Control Services |
| MCS | Modular Causeway Section |
| MCS | Maintenance Cost System |
| MCS | Multi-functional Crypto System |
| MCS | Master Control Shelf (Nokia) |
| MCS | Multimedia Computer System |
| MCS | Meteorological Services of Canada |
| MCS | Magnetic Core Stack |
| MCS | Mountaineering Club of Scotland |
| MCS | Meaford Community School |
| MCS | Mining Certification Service (United Kingdom) |
| MCS | Maintenance Control Station |
| MCS | Micro Controller Subsystem |
| MCS | Mobile Command Station |
| MCS | Mesa Computing Solutions (Grand Junction, Colorado) |
| MCS | Mission Critical Site |
| MCS | Multi-Programmed Computer System |
| MCS | Mandala Complementary Studies (UK Complementary Therapy School) |
| MCS | Managing Conceptual Space |
| MCS | Microchannel Structure |
| MCS | Mellor-Crummy and Scott Algorithm |
| MCS | Microcrystalline Cellulose, Sieved |
| MCS | Microcontrol Store |
| MCS | Modernized Catalog System |
| MCS | Mine Command Ship |
| MCS | Crew Station Manual (TMINS) |
| MCS | Millimeter Wave Contrast Seekers |
| MCS | Multiple Congestion States (ITU-T) |
| MCS | Multi-Cast Send |
| MCS | Missing Case Statements in A Switch Construct (software fault) |
| MCS | Madeley Court School (UK) |
| MCS | Merrimack Charter Services |
| MCS | Moisture Channel Support |
| MCS | Multi-Purpose Communications & Signaling |
| MCS | Master of the Cheirological Society of Great Britain |
| MCS | Mine Countermeasures Ship/Support |
| MCS | Missile Compensating System |
| MCS | Mission Control Segment/System |
| MCS | Managed Clearline Service (Sprint) |
| MCS | Maneuver Computer System |
| MCS | Moto Club Sommièrois (French motorcycle club) |
| MCS | Mobility Concepts Study |
| MCS | Material Certification System |
| MCS | Multicultural Council of Saskatchewan (also seen as MCOS; Canada) |
| MCS | Matra Club Suisse (French: Switzerland Matra Club; automobile club; Switzerland) |
| MCS | Management Challenge Services |
| MCS | Multichannel Streamer (natural gas exploration) |
| MCS | Multiple Circular Sectors (microwave hardware) |
| MCS | Mobile Communications Solutions (UK and Ireland) |
| MCS | Marietta City Schools (Georgia) |
| MCS | Mercury Computer Systems (various locations) |
| MCS | Medium Close Shot (videography) |
| MCS | Motor Cortex Stimulation (neurology) |
| MCS | Machine Coordinate System (manufacturing) |
| MCS | McMaster-Carr Supply (Elmhurst, IL) |
| MCS | Multichannel Seismic (natural gas exploration) |
| MCS | Montgomery County Schools (various locations) |
| MCS | Microbial Culture and Sensitivity (test) |
| MCS | Managed Communication Services |
| MCS | Mobile Communications System (various organizations) |
| MCS | Massachusetts Chiropractic Society (Methuen, MA) |
| MCS | Multichannel Scaler (natural gas exploration) |
| MCS | Maximal Common Substructure |
| MCS | Mayo Clinic Study |
| MCS | Manager, Client Services (various organizations) |
| MCS | Manhattan Country School (New York) |