| Acronym | Definition |
|---|
| MSM | Mainstream Media |
| MSM | Men who have Sex with Men (health/medical) |
| MSM | Methylsulfonylmethane |
| MSM | Morehouse School of Medicine |
| MSM | Muscat Securities Market (Oman) |
| MSM | Men Seeking Men |
| MSM | Mobile Station Modem (Qualcomm) |
| MSM | Manhattan School of Music |
| MSM | Mobile Suit (Marine; Gundam gaming) |
| MSM | Meritorious Service Medal |
| MSM | Metal-Semiconductor-Metal (photodetector) |
| MSM | Miami Sound Machine (band) |
| MSM | Microsoft Solutions for Management |
| MSM | Militant Socialist Movement (Mauritius) |
| MSM | Mechanically Separated Meat |
| MSM | Masters of Science in Management |
| MSM | Missouri School of Mines |
| MSM | Multilayer Switch Module (Cisco) |
| MSM | MSM Security Services Inc. |
| MSM | Marine Safety Manual |
| MSM | Mirror, Signal, Manoeuvre |
| MSM | Minimal Standard Model |
| MSM | Master of Science in Marketing |
| MSM | Microwave Switch Matrix (satellites) |
| MSM | master-slave manipulator |
| MSM | Management Switch Fabric Module (Extreme Networks) |
| MSM | Multiservice Module (Anymedia) |
| MSM | Mass Storage Module (IBM) |
| MSM | Marché Suisse des Machines |
| MSM | Methodist Student Movement |
| MSM | Multiple Subcarrier Modulation |
| MSM | Minesweeper, River |
| MSM | Memory Seat Module (General Motors) |
| MSM | Military Service Medal |
| MSM | Memory-Space-Memory |
| MSM | Mazda Speed Miata |
| MSM | Message Stream Modification |
| MSM | Miami Science Museum |
| MSM | Mission Space Model |
| MSM | Mid-Span Meet |
| MSM | Management/Switching Module |
| MSM | Madras and Southern Maratha (railroad) |
| MSM | Mode Select Mechanism |
| MSM | Mahavir Spinning Mills Ltd |
| MSM | Multiple Space-Mapping |
| MSM | Master of Security Management |
| MSM | Mount Saint Mary's School (Delhi, India) |
| MSM | Mount Saint Mary's College and Seminary |
| MSM | Mission Services Manager |
| MSM | Marketing Strategies Management |
| MSM | Major System Mode |
| MSM | Mid-Systolic Murmur |
| MSM | Maintenance Service Module |
| MSM | Move & Store Material |
| MSM | Movimiento de los Sin Miedo (Bolivia, Movement Without Fear) |
| MSM | Matrix Switch Module |
| MSM | Maintenance Support Material |
| MSM | Minimum Science Mission |
| MSM | Master in Services Management |
| MSM | Munition Service Magazine |
| MSM | Master Structure Management |
| MSM | Maritime Safety Management |
| MSM | McAfee System Management |
| MSM | Maktab Sains Mara |
| MSM | Multiple Session Menu |