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Primary parathyromatosis occurs in patients with multiple endocrine neoplasia (MEN), most commonly MEN type 1. Familial multiple endocrine neoplasia type 1 (FMEN1) is an inherited disorder that affects the endocrine glands. It has been reported that patients with a history of familial hyperparathyroidism, (8) multiple endocrine neoplasia syndrome type I, (9) and hereditary hyperparathyroidism--jaw tumor syndrome (10) are more predisposed to developing parathyroid carcinoma. |
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