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MPO |
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We evaluated the number of rolling and adherent leukocytes in spinotrapezius muscle venules, lung histology, muscle histology, microvascular mRNA levels, myeloperoxidase (MPO) deposition, and oxidative stress in the spinotrapezius muscle microvascular wall. Chloroma (chlor = green, oma = tumor) is an old clinical term that refers to the green hue identified in fresh specimens as a result of myeloperoxidase production. The trial is designed to examine the effect of various doses of DG031 on biomarkers such as C-reactive protein (CRP) and myeloperoxidase and on the production of leukotrienes. |
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