N-9


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AcronymDefinition
N-9Nonoxynol9 (spermicide)
References in periodicals archive ?
The primary goal of this multicenter, randomized clinical trial was to compare the efficacy of different N-9 spermicide formulations.
Christine Mauck said these findings are consistent with earlier observations that the differences in lesions between placebo and N-9 are seen only in frequent users.
Christine Mauck commented that the findings are consistent with earlier observations that the differences in lesions between placebo and N-9 are seen only in frequent users.
We are concerned that many people mistakenly believe that N-9 provides extra protection against HIV and STDs when used rectally when in fact there is reason to think that rectal use of N-9 may increase risk of infection.
Therefore, N-9 should not be used as a microbicide or lubricant during anal sex.
Data on the percentage of condoms lubricated with N-9 were not available.
Editorial Note: The findings in this report indicate that in 1999, before the release of recent publications on N-9 and HIV/STDs (4,6,7), Title X family planning clinics in the U.
Centers for Disease Control and Prevention (CDC) published similar recommendations, advising family planning providers to inform women at risk of HIV and other STIs that N-9 spermicides do not protect against these infections.
The WHO and CDC recommendations are based, in part, on an analysis of 10 randomized clinical trials of the effectiveness of N-9 against HIV or other STIs, involving almost 5,000 women, that included trials conducted by the Joint United Nations Programme on HIV/AIDS (UNAIDS) and FHI.
Now that there is a clear, official consensus that N-9 is harmful, especially for rectal use, it is likely to start disappearing from condoms and lubes.
We are concerned that many people mistakenly believe that N-9 provides extra protection against HIV and STDs when studies show that N-9 increases risk of infection when it is used rectally," said Lori Heise, Director of the Global Campaign for Microbicides, the group spearheading the "Call to Discontinue N-9 for Rectal Use.
If it also provided effective protection against HIV in clinical studies, N-9 could be made rapidly available to women who require protection.