NHEJNon-Homologous End Joining
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Xia said that the study produced biochemical and genetic evidence that radiation-induced DSBs were repaired with greater efficiency in lithium-treated cells via the NHEJ pathway.
By contrast, failed NHEJ repair has no effect on chromosomal aberrations (66).
And since the cell uses NHEJ only when many cells are becoming specialized, cancers that arise in the absence of this pathway are more specific, such as cancer of a type of cell that produces only immune cells called B lymphocytes.