NIPBL - What does NIPBL stand for? The Free Dictionary
Also found in: Wikipedia
|NIPBL||Nipped-B-Like (Delangin homolog)|
References in periodicals archive
Recruitment of the cohesin loading factor NIPBL
to DNA double-strand breaks depends on MDC1, RNF168 and HP1y in human cells.
The researchers showed in cell cultures that mutations in HDAC8 lead to a decrease in cohesin binding to genes, similar to that seen for cells deficient in the NIPBL
In contrast to the NIPBL
gene, in which mutations cause roughly half of known CdLS cases, the researchers found that mutations in the new genes, SMC3 and SMC1A, cause only about 5 percent of CdLS cases.
stands for Nipped B-like, because the human gene produces proteins similar to those produced by the Nipped-B gene in fruit flies.