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NMRI |
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To isolate TBEV strains from the RT-PCR-positive tick pools, 20 [micro]L of the supernatant of the pools diluted 1:1 in D-PBS-BSA was injected intracerebrally into suckling NMRI mice. A single oral dose of PBDE-99 (12 mg/kg body weight) or vehicle was administered to male NMRI mice on neonatal day 10, and the striatum and the hippocampus were isolated. The authors conclude that NMRI is potentially useful as a non-intrusive, quantitative measure of dispersion monitoring method that possibly can be used on-line. |
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