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This applies to all agents, not just medications with a narrow therapeutic index such as digoxin, warfarin, theophylline and phenytoin. On a monthly basis, medication use and cost was measured and reported the number of medications and medication doses per nursing home resident per month; the number of laboratory measurements for narrow therapeutic index drugs per nursing home resident per month; and the cost of all oral medications per nursing home resident per month. As such, CGX-1160 could provide physicians and patients with the "next generation" of conopeptide-based analgesics that have been designed to address safety considerations, such as narrow therapeutic index, inherent in first-generation conopeptides for pain management. |
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