| Acronym | Definition |
|---|
| NPI | No Pun Intended |
| NPI | Not Plugged In (computer/network technical problem) |
| NPI | National Provider Identifier |
| NPI | New Product Introduction |
| NPI | Northwest Progressive Institute |
| NPI | Non-public Personal Information |
| NPI | Norwegian Polar Institute (Norway) |
| NPI | Neuropsychiatric Institute (UCLA) |
| NPI | Narcissistic Personality Inventory |
| NPI | New Partners Initiative (est. 2005) |
| NPI | Net Profits Interest |
| NPI | National Productivity Institute (South Africa) |
| NPI | National Preservation Institute |
| NPI | Negative Polarity Item (linguistics) |
| NPI | Numbering Plan Indicator |
| NPI | Network Printer Interface |
| NPI | Norsk Polarinstitutt (Norway) |
| NPI | Non-Profit Institution |
| NPI | Nickel Pig Iron |
| NPI | Non-Personal Information |
| NPI | Non-Pharmaceutical Intervention (infectious disease control strategy) |
| NPI | Neuro Psychiatric Inventory |
| NPI | Neutral Particle Imager |
| NPI | National Procedures Institute (Midland, MI) |
| NPI | Network Provider Interface |
| NPI | No Poseo Información |
| NPI | Novos Países Industrializados (newly industrialized countries) |
| NPI | Non-Precision Instrument |
| NPI | New Patient In |
| NPI | Nordpol Innsbruck (FCW fanclub) |
| NPI | Nonpublic Personal Member Information |
| NPI | Network Provisioning Interface |
| NPI | NROS Predictive Index (NASCAR Racing Online Series game) |
| NPI | Non Policy Issuance (insurance) |
| NPI | Not Pre-Installed |
| NPI | New Product Initiative (various companies) |
| NPI | National Pollutant Inventory (Australia) |
| NPI | National Polytechnic Institute (various locations) |
| NPI | New Politics Institute (various locations) |
| NPI | No Punt Intended (fantasy football) |
| NPI | Nextel Partners, Inc. (wireless telecommunications joint venture) |
| NPI | Natural Products, Inc. (Grinnell, IA) |