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If a similar study were conducted with general patients with lumbar degenerative diseases, it is thought that the prevalence and the positive predictive value would decrease and the negative predictive value would increase. Laboratory professionals were specifically trained about the sensitivity, specificity, positive predictive value, and negative predictive value of test methods in relation to sample type, time between symptom onset and specimen collection, and disease prevalence. We consider a framework for detection and judgment of evidence of well-characterized hazards, using the concepts of sensitivity, specificity, positive predictive value, and negative predictive value that are well established for medical diagnosis. |
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