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Stenting induces a proliferative response, sometimes producing enough neointimal hyperplasia within the lumen of the stent to obstruct flow. Elixir Medical's Novolimus Eluting Coronary Stent system was effective in reducing lumen loss and neointimal hyperplasia at four-month angiographic follow-up in patients treated with the device. on their discovery of the role of the intracellular protein R-Ras in neointimal hyperplasia, angiogenesis and vascular proliferation. |
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