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Parameters of neuraminadase inhibitor stockpiling strategies model * Minimum ([double Parameter Notation ([dagger]) dagger]) Input General population [N. Comparison of influenza viruses (a) Characteristic Influenza A Influenza B Genome Negative-strand RNA, Negative-strand RNA, eight segmented genes eight segmented genes Sequence High Moderate variability in HA and NA Mode of antigen Antigenic drift and Antigenic drift only variation antigenic shift Hosts Humans, avian, swine, Humans only equine, marine mammals Epidemiology Epidemic, pandemic Epidemic, nonpandemic (a) RNA, ribonucleic acid; HA, hemagglutinin; NA, neuraminadase. Sequencing and phylogenetic analysis of the hemaggluttinin (HA) and neuraminadase (NA) genes of the dog's virus showed that they were similar to those of H5N1 viruses isolated from tigers, chickens, ducks, and humans infected in Thailand during the same time that the dog was infected (Figure 2A and B). |
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