| Acronym | Definition |
|---|
| NIS | Norton Internet Security (Symantec software) |
| NIS | Newly Independent States |
| NIS | Naval Investigative Service |
| NIS | Network Information Service (aka Yellow Pages) |
| NIS | Network Information Services |
| NIS | Network Information System |
| NIS | New Independent States |
| NIS | National Immunization Survey |
| NIS | Nippon Ichi Software |
| NIS | Nationwide Inpatient Sample |
| NIS | New Israeli Shekel (currency in Israel) |
| NIS | National Intelligence Service (various countries) |
| NIS | Sodium Iodide Symporter |
| NIS | National Information System |
| NIS | National Information Service (various countries) |
| NIS | National Institute of Sports (India) |
| NIS | Not in Service |
| NIS | Not In Stock |
| NIS | Norsk Internasjonalt Skipsregister (Norwegian International Ship Registery) |
| NIS | Navigation Information Service (US DoT) |
| NIS | Network Infrastructure Solutions |
| NIS | Nonproliferation and International Security division (US DOE) |
| NIS | Nishimachi International School (Tokyo, Japan) |
| NIS | National Insurance System |
| NIS | NATO Identification System |
| NIS | National Implementation Strategy |
| NIS | National Intelligence Strategy |
| NIS | Non-Interactive Sequence (gaming) |
| NIS | Nuclear Instrumentation System |
| NIS | Non-Proliferation and International Security |
| NIS | NATO International Staff |
| NIS | National Input Segment |
| NIS | National Intelligence System |
| NIS | Neurological Impairment Scale |
| NIS | National Integration Services (touchscreen manufacturer) |
| NIS | Neighborhood Improvement Strategy |
| NIS | Noise Information System |
| NIS | New Immigrant Study |
| NIS | Network Integrity Services Ltd (Stockport, Cheshire, UK) |
| NIS | Net Interest Spreads |
| NIS | Non-Invasive Sampling |
| NIS | National Imagery System |
| NIS | National Interdepartmental Seminar |
| NIS | NIMA Information Service |
| NIS | Nitrogen Inerting System (military aviation, fuel subsystem) |
| NIS | NMCS Information System (US DoD) |
| NIS | National Insurance Specialists |
| NIS | Nestlé Investor Seminar |
| NIS | Negotiation Information System |
| NIS | National Intelligence Survey |