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References in periodicals archive ?
1) The next therapeutic choice was a non-myeloablative stem-cell transplant.
Gopal's ASH presentation is entitled Y-90 Ibritumomab Tiuxetan, Fludarabine, and TBI Based Non-Myeloablative Allogeneic Transplant Conditioning for High-Risk B-Cell Lymphoma.
The incidence of POF is lower in cases treated with non-myeloablative conditioning regimens and autologous transplantation (33).
For the first time, we were able to achieve engraftment, a state of mixed chimerism, and durable remissions in patients with refractory hematologic malignancies after a non-myeloablative transplant regimen," said Thomas Spitzer, MD, director of MGH's bone marrow transplant program, in a report published in the May 22nd issue of The Lancet.
We have previously reported the adverse prognostic value of PET+ in autologous transplants (AUTO) and disease refractoriness in pts undertaking a non-myeloablative allogeneic transplantation (NST).
Some progress has been demonstrated recently by using a less aggressive, non-myeloablative preparative regimen, followed by an infusion of unmanipulated bone marrow and the post-transplant use of a common chemotherapy drug, cyclophosphamide (Cy), but relapse is relatively common, especially in those with high-risk myeloid malignancies.
The demonstration of successful reversal of the disease using purified stem cells with non-myeloablative conditioning offers a novel strategy to treat autoimmune diseases such as lupus with decreased morbidity," said Ramkumar Mandalam, Ph.
Tandem Autologous Hematopoietic Stem Cell Transplants (AuHCT) With or Without Maintenance Therapy (auto-auto) Versus Single AuHCT Followed by HLA Matched Sibling Non-Myeloablative Allogeneic HCT (auto-allo) for Patients With Standard Risk (SR) Multiple Myeloma (MM): Results From the Blood and Marrow Transplant Clinical Trials Network (BMT CTN) 0102 Trial [Abstract 41]
His current research interests include the investigation of non-myeloablative conditioning prior to allogeneic transplantation and the use of allogeneic and autologous hematopoietic transplantation for hematologic malignancies and selected solid tumors.
Rosenberg has identified and characterized a number of melanoma tumor-associated antigens, including gp100 and MART-1, and has developed a lymphodepleting non-myeloablative regimen used for adoptive cell therapy (ACT).
Matched Unrelated Donor (MUD) BMT Abstract #2515 -- Unrelated Donor Hematopoietic Stem Cell Transplantation after Administration of a Non-Myeloablative Conditioning Regimen of Fludarabine, Rabbit Anti-Thymocyte Globulin (rATG), and Total Body Irradiation (TBI).
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