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NASH |
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The primary indication for BL-1060 is fatty liver disease (including nonalcoholic steatohepatitis or NASH), which is associated with the near epidemic of obesity and diabetes. It is also been shown that this oxidative stress and inflammation are significant problems leading to disease progression in the livers of patients with chronic hepatitis C, alcoholic liver disease (ALD) and nonalcoholic steatohepatitis (NASH). Based upon the basic mechanism of action of histamine therapy, and the results seen in clinical and preclinical testing, Maxim intends to further explore the testing and development of histamine in chronic liver diseases such as hepatitis C and nonalcoholic steatohepatitis (NASH). |
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