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The researchers used one microelectrode to detect dopamine and to measure its concentration fluctuations in the nucleus accumbens, located toward the front of the brain. Subsets of dams and offspring were sacrificed at postnatal day (PN)1 and at day 21 for determinations of BPb levels (dams only) and for determinations of neurotransmitter levels in frontal cortex, striatum, and nucleus accumbens (day 21 only for offspring). Scientists have identified a reward pathway in the brain that includes the nucleus accumbens. |
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