| Acronym | Definition |
|---|
| OTD | Of the Day |
| OTD | Out The Door |
| OTD | Office of Technology Development |
| OTD | On the Door |
| OTD | Doctor of Occupational Therapy |
| OTD | On Time Delivery |
| OTD | Overseas Trained Doctor |
| OTD | Observed Time Difference |
| OTD | Optical Transient Detector |
| OTD | Order-To-Delivery |
| OTD | Occupational Therapy Doctorate |
| OTD | Open Technology Development |
| OTD | Open the Door (social networking website) |
| OTD | Office of The Director |
| OTD | Office of Tourism Development (Maryland) |
| OTD | Older Than Dirt |
| OTD | On the Double |
| OTD | Orthogonal Transmit Diversity |
| OTD | Ornithine Transcarbamylase Deficiency |
| OTD | Operational Test Director |
| OTD | Object Type Definition (Java) |
| OTD | Old Telephone Directories (pulp and paper industry) |
| OTD | Open Technical Dictionary (Electronic Commerce Code Management Association) |
| OTD | Oakland Touchdown (bridge building project; California) |
| OTD | Off Topic Discussion (forums/newsgroups) |
| OTD | On the Dot |
| OTD | Ottawa Therapy Dogs (Canada) |
| OTD | Obsessive Twilight Disorder |
| OTD | Oculotrichodysplasia |
| OTD | Old Tablers Deutschland (Germany) |
| OTD | One Touch Down (automotive power window function) |
| OTD | Obsessive Twitter Disorder |
| OTD | Organ Tolerance Dose |
| OTD | Official Test Day (pregnancy) |
| OTD | Ours To Destroy (band) |
| OTD | Off the Derech |
| OTD | Oh, The Drama |
| OTD | Operations & Training Division |
| OTD | Operator Trunk Dialing (telecommunications) |
| OTD | Orally Transmitted Diseases |
| OTD | One Time Developed |
| OTD | On-Time Departure (airlines) |
| OTD | Operations Training Directorate |
| OTD | Organizational Theory and Dynamics |
| OTD | Offer to Dedicate (California) |
| OTD | Off the Dock Toons (comic strip series) |