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OPG |
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It also prevents bone breakdown by limiting parathyroid hormone, the hormone primarily responsible for releasing calcium from bone into the bloodstream, and by stimulating osteoprotegerin, the potent inhibitor of bone restoration. Serum levels of receptor activator of nuclear factor-kappaB ligand (RANKL) and osteoprotegerin (OPG) were measured. The intratympanic corticosteroids might have produced a permanent hearing loss as a result of their effect on osteoprotegerin in the inner ear. |
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