| Acronym | Definition |
|---|
| OSR | Orchestre de La Suisse Romande |
| OSR | OEM Service Release |
| OSR | Ontario Student Record |
| OSR | Office of School Readiness (various locales) |
| OSR | Open Systems Resources, Inc (Amherst, NH) |
| OSR | Operating Systems Review (ACM) |
| OSR | Oversampling Ratio |
| OSR | Office of Scientific Research |
| OSR | Ohio State Reformatory |
| OSR | Overseas Service Ribbon |
| OSR | Old San Antonio Road |
| OSR | Optical Solar Reflector |
| OSR | On-Site Representative |
| OSR | Organization Systems Renewal |
| OSR | Optical Scanning Recognition |
| OSR | Operational Safety Requirement |
| OSR | Organization for SETV Research |
| OSR | Ontario Southland Railway, Inc. |
| OSR | Optical Service Router (Cisco Systems) |
| OSR | Operational Safety Review |
| OSR | Optimized Set Reduction |
| OSR | Oxidative Stress Relief |
| OSR | One-Shot Rising |
| OSR | Office of Systems Requirements |
| OSR | Occupational Survey Report |
| OSR | Ostrava Mosnov Czech Republic (airport code) |
| OSR | Official Site Register |
| OSR | Organisation Syndicale Représentative |
| OSR | Ockanickon Scout Reservation (Pennsylvania Boy Scout Camp) |
| OSR | Optical Subrack |
| OSR | Over Subscription Ratio |
| OSR | Onteora Scout Reservation (Livingston Manor, NY) |
| OSR | On-Scene Representative |
| OSR | Optimized Sniper Rifle (LaRue Tactical) |
| OSR | One Step Routing |
| OSR | Operational Support Requirement |
| OSR | Office of Standards and Regulation |
| OSR | Officer Selection Report |
| OSR | Optimum Sonar Routing |
| OSR | Outlet Sales Report |
| OSR | Oscillator Statistics Request |
| OSR | Order of the Silver Ribbon |
| OSR | Out of Service Repair Tag (mining maintenance industry for sending repairable items off site and keep) |