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PANSSPositive and Negative Syndrome Scale (schizophrenia)
PANSSPositive and Negative Symptoms Score
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The positive symptom scores of the PANSS scale were negatively correlated with the Gln concentration in the anterior cingulate cortex (r=-0.
Current smokers obtained statistically significant higher scores on the PANSS than nonsmokers.
Besides, in our study, the lack of correlation between ToM functions and cognitive flexibility instead of PANSS that assesses symptom severity may have a contribution to arguments that ToM functions and cognitive flexibility are among the core symptoms of schizophrenia.
Spearman correlational analyses were conducted to investigate relationships between PTI total and subcategory scores, PANSS factor-derived scores and MCCB composite and domain scores.
In addition, the ROI-based correlation analyses with PANSS scores were performed for the two patient groups using a partial correlation analysis while controlling for age and sex.
PANSS is a 30-item rating instrument evaluating the presence/absence and severity of positive, negative and general psychopathology of schizophrenia.
Efficacy was measured primarily as change in total PANSS score from the baseline to day 85 (4,5); secondary efficacy variable was the CGI-I score at day 85.
Table 1 shows the demographic characteristics and diagnoses of the sample, as well as mean scores on the PANSS subscales.
La escala de psicopatologia general de la PANSS engloba sintomatologia de ansiedad y depresion, que se relaciona con baja autoestima (Jones, Hansen, Moskvina, Kingdon y Turkington, 2010), Aunque esta significacion desaparece cuando se hace la correccion por comparaciones multiples, consideramos conveniente la utilizacion de pruebas de evaluacion mas especificas y detalladas sobre ansiedad y depresion.
Third, future studies should explore important variables such as the years of evolution of the disorder and the severity of disorder that we could not include in our analyses because of the problem of colinearity with variables such as patients' age, caregivers' age and cognitive PANSS.
In recent years, the application of PANSS has gradually increased for the evaluation of psychological symptoms and their severity in patients with schizophrenia [11-15].