PFWTPain-Free Walking Time
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Compared with the placebo group, those in the ramipril group had a mean PFWT increase of 75 seconds (95% CI, 60-89; P<.
The pilot study showed average gains of 164% in PFWT and 243% in MWT with 24 weeks of ramipril, a magnitude of benefit roughly twice that seen in the new, much larger trial.
Outcomes in the two randomized trials of ramipril for PAD - gains of 87%-164% in PFWT and 139%-243% in MWT - compare favorably with the results of placebo-controlled studies of conventional therapies.