| Acronym | Definition |
|---|
| PLC | Public Limited Company (UK) |
| PLC | Phospholipase C |
| PLC | Product Life Cycle |
| PLC | Parti Liberal du Canada |
| PLC | Psycho Le Cemu (Japanese band) |
| PLC | Palestinian Legislative Council |
| PLC | Powerline Communication |
| PLC | Professional Learning Community (education) |
| PLC | Programmable Logic Control(ler) |
| PLC | Public Service Commission (Canada) |
| PLC | Power Line Carrier (using power lines to carry data/voice signals) |
| PLC | Publicly Listed Company |
| PLC | Planar Lightwave Circuit |
| PLC | Project Life Cycle |
| PLC | Partido Liberal Constitucionalista (Constitutional Liberal Party; Nicaragua) |
| PLC | Packet Loss Concealment |
| PLC | Puerto La Cruz (Venezuela) |
| PLC | Patrol Leaders' Council (Boy Scouts of America) |
| PLC | Presbyterian Ladies' College (Australia) |
| PLC | Personal Line of Credit |
| PLC | Perlecan |
| PLC | Partners for Livable Communities |
| PLC | Positive Living Centre (Australia) |
| PLC | Platoon Leaders Class |
| PLC | Park Lane College (UK) |
| PLC | Professional Limited Liability Company |
| PLC | Private Label Card |
| PLC | Power Line Conditioner |
| PLC | Private Leased Circuit |
| PLC | Portevin le Chatelier (Effect) |
| PLC | Polymer Liquid Crystal |
| PLC | Professional Loss Control |
| PLC | Presidents Leadership Class (undergraduate leadership development program, University of Colorado, Boulder) |
| PLC | Payload Commander (NASA) |
| PLC | Programmable Logic Circuit |
| PLC | Program Leadership Committee |
| PLC | Preparative Liquid Chromatography |
| PLC | Platoon Leader's Course (USMC Officer Program) |
| PLC | Power Line Coupler |
| PLC | Process Loop Control |
| PLC | Primary Leadership Course (US Army) |
| PLC | Pigmented Lesion Clinic |
| PLC | Pakistan Law Commission |
| PLC | Platform LAN Connect Device (Intel Pentium processors) |
| PLC | Performance Level Category |
| PLC | Pneumatic Logic Control (Houston, TX) |
| PLC | Posterior Lateral Complex (ligament in knee) |
| PLC | Program Level Change (tape) |
| PLC | Public Level Crossing |
| PLC | Program Leaders Committee |
| PLC | Phase-Locked Clock |
| PLC | Projected Line Charge |
| PLC | Pathetic Losers Club |
| PLC | Progressive Learning Center |
| PLC | Princeton Listening Center |
| PLC | Post Literacy Class |
| PLC | Proto-Lower Cross |
| PLC | Pressurized Logistic Carrier |
| PLC | Peace, Love, and Care |
| PLC | Post-Lunch Coma |
| PLC | Programming Language Committee |
| PLC | Project Launch Coordinator |
| PLC | Power Level Controller |
| PLC | Point of Last Contact |
| PLC | Partners in a Learning Community |
| PLC | Pilot Lighting Control (aviation) |
| PLC | Potomac Literary Club |
| PLC | Preliminary Load Cycle |
| PLC | Program Library Control |
| PLC | Partial Loss of Capacity (SDH or Sonet Technology) |
| PLC | Pendulum Live Community |
| PLC | Philip Leverhulme Centre (Reaseheath College, England) |