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PP2A

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AcronymDefinition
PP2AProtein Phosphatase 2A


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Byline: ANI Washington, June 23 (ANI): Researchers at Duke-NUS Graduate Medical School in Singapore have identified a tumour-suppressing protein in the brains of fruit flies, called PP2A (protein phosphatase 2A), which has a counterpart in mammals.
Elizabeth O'Hearn, MI Johns Hopkins School of Medicine Spinocerebeilar Ataxia Type 12 (SCA 12): Investigate PP2A Relation of Group I Metabotropic Receptors Spinocerebellar ataxia type 12 (SCA12) is an autosomal dominant (AD) neurologic disorder in which tremor and ataxia are prominent signs.
Recombinant PME-1 polypeptide produced in bacteria demethylates PP2A C subunit in vitro and okadaic acid, a known inhibitor of the PP2A methylesterase, inhibited this reaction.
 
 
 
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