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PP2A |
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Byline: ANI Washington, June 23 (ANI): Researchers at Duke-NUS Graduate Medical School in Singapore have identified a tumour-suppressing protein in the brains of fruit flies, called PP2A (protein phosphatase 2A), which has a counterpart in mammals. Elizabeth O'Hearn, MI Johns Hopkins School of Medicine Spinocerebeilar Ataxia Type 12 (SCA 12): Investigate PP2A Relation of Group I Metabotropic Receptors Spinocerebellar ataxia type 12 (SCA12) is an autosomal dominant (AD) neurologic disorder in which tremor and ataxia are prominent signs. Recombinant PME-1 polypeptide produced in bacteria demethylates PP2A C subunit in vitro and okadaic acid, a known inhibitor of the PP2A methylesterase, inhibited this reaction. |
PP2A |
PP&L PP&M PP&O PP&P PP&R PP&SC PP&SL PP-1 PP-AC PP-MRD-CI PP-oma PP-PI pp. pp. PP/DP Pp/Sp Pp1 PP10 PP120 PP13 PP17 PP18a PP1c PP1G PP2 PP2A PP2AcPP2B PP2C PP3 pp39 PP4 PP4SD PP5 pp50 PP55 PP6 PP96 PPA PPA PPA PPA-GKC PPA-LCI PPAA PPAAC PPAB PPABC PPAC PPACA PPACG PPACK PPAD | |||||
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