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PP2C

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AcronymDefinition
PP2CProtein Phosphatase 2C


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In the absence of ABA, the hand remains open, but when ABA is present it nestles in the palm of the PYR1 hand, which closes over the hormone as if holding a ball, thereby enabling a PP2C molecule to sit on top of the folded fingers.
PPMD1, a member of the PP2C family of Ser/Thr protein phosphatases that is induced in a p53-dependent manner in response to various environmental stresses, reduces the phosphorylation of p53 through negative regulation of p38 MAP kinase, and in turn suppresses p53-mediated transcription and apoptosis (Bulavin et al.
 
 
 
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