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PP2C

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AcronymDefinition
PP2CProtein Phosphatase 2C


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PPMD1, a member of the PP2C family of Ser/Thr protein phosphatases that is induced in a p53-dependent manner in response to various environmental stresses, reduces the phosphorylation of p53 through negative regulation of p38 MAP kinase, and in turn suppresses p53-mediated transcription and apoptosis (Bulavin et al.
Profiles of global gene expression in ionizing-radiation--damaged ... by Kaufmann, William K / Environmental Health Perspectives
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