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PPAR |
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The test articles included two marketed peroxisome proliferator [alpha]-agonists (PPAR[alpha]; fenofibrate and ciprofibrate) and a proprietary PPAR panagonist compound (PPARpan) with activity on PPAR [alpha], [gamma] and [sigma] receptors. JANUVIA has also been studied as add-on therapy with PPAR agonists in patients with type 2 diabetes in whom use of a PPAR agonist (e. After identifying expression profiles in Wistar rats induced by several peroxisome proliferator-activated receptor (PPAR) agonists, the SVM was used to look at data for the livers of Sprague-Dawley rats exposed to another PPAR agonist, WY14643. |
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