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PSEN1

   Also found in: Wikipedia 0.02 sec.
AcronymDefinition
PSEN1Presenilin 1


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Scott is, however, a little relieved because Emily does not carry her mum's defective PSEN1 gene that would have predisposed her to Alzheimer's.
These possible "loss of function" PSEN1 mutations might act as inhibitors of the [gamma]-secretase cleavage of amyloid precursor protein (27), leading to a decrease of A[beta] (1-42) in the brain.
 
 
 
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