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PXR

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AcronymDefinition
PXRPregnane X Receptor
PXRPost Exercise Report
PXRPixar File Format
PXRPost Exercise Review


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? References in periodicals archive
We found that certain highly chlorinated PCBs are potent activators of rodent PXR but antagonize its human ortholog, the steroid and xenobiotic receptor (SXR), inhibiting target gene induction.
Highly chlorinated PCBs inhibit the human xenobiotic response ... by Blumberg, Bruce / Environmental Health Perspectives
The scientists discovered that the most stable and abundant PCBs found in human tissues activated PXR and induced expression of target genes for metabolizing the toxicants, producing a protective physiological reaction in rodents.
The danger of extrapolation: humans and rodents differ in response to ... by Eubanks, Mary / Environmental Health Perspectives
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