PaO2/FIO2Pressure of Arterial Oxygen to Fractional Inspired Oxygen Concentration
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In our patient, the findings from the second lung X-ray, the bilateral alveolar interstitial infiltrates and the severe hypoxemia with PaO2/FIO2 no higher than 200 were compatible with ARDS.
The PaO2/FiO2 index quantifies the relationship between arterial oxygen tension and available oxygen concentrations.
23 identified a PaO2/FiO2 ratio of 350, Horowitz index).
Comparing to the preoperative day, the IAP decreased markedly, the urine output increased to more than 3000ml on the 7th postoperative day, tidal volume, Peak airway pressure (PAP) and PaO2/FiO2 was improved satisfactorily (Table-I).
It is also found in published studies that ventilation with low tidal volume (3ml/kg) without PEEP per CPB could not significantly change pulmonary vascular resistance index (PVRI), mean pulmonary artery pressure (MPAP), pulmonary complications, PaO2/FiO2 ratio and total length of stay12-14.
Respiratory failure was defined as failure to maintain PaO2/FiO2 ratio at 200 or above.
Descriptive statistics were used to calculate mean and standard deviation for age, PaO2/FiO2, ribs fracture and lung contusion.
In addition to the co-morbidities, presence or absence of septic shock and acute kidney injury, PaO2/FiO2 ratio and type of mechanical ventilation were recorded on ICU admission.
As far as ABG values were concerned, in our study we found that lower PaO2/FiO2 values were associated with increase in mortality.
The PaO2/FiO2 ratio was below 60 despite optimum ventilator settings during at least 16 hours (Table).
IS group patients had better PaO2/FiO2 ratio of 395 +- 95, 359 +- 93 and 334 +- 59 at extubation, 6 hours after extubation and 24 hours after surgery respectively than that of 317+- 73, 307 +- 89 and 301 +- 34 in the NIS group.
DEFINITION: "Adult Respiratory Distress Syndrome (ARDS) is a form of Acute & Persistent respiratory failure, which Radiographically presents as bilateral pulmonary infiltrates with the presence of edema & associated impaired oxygenation regardless of the PEEP concentration, to Pao2/fio2 [less than or equal to] 200, excluding clinical evidence of left atrial hypertension or pulmonary--artery catheter occlusion pressure of [greater than or equal to] 18 mm of Hg.