In a study analyzing data collected from 8,105 HBsAg-negative infants born to HBsAg-positive mothers enrolled in the Enhanced Perinatal Hepatitis B Prevention Program in five U.
New data from the Enhanced Perinatal Hepatitis B Prevention Program are available that show that lower detectable levels of anti-HBs were associated with increased intervals between receipt of the last vaccine dose and PVST.
The existence of a National Perinatal Hepatitis B Prevention Program
to support immunization programs in performing active identification of infants born to women infected by hepatitis B virus (HBV) provided an opportunity to compare the number of HBV-infected infants identified actively through the immunization programs with the number of HBV-infected infants identified passively through communicable disease surveillance.
Among infants born to HBsAg-positive mothers and managed by perinatal hepatitis B prevention programs
in the United States, and who received >3 HepB doses, PVST rates by age 15-27 months increased from 25% in 1994 to 56% in 2008 (1).