| Acronym | Definition |
|---|
| PSF | Python Software Foundation |
| PSF | Programa Saude da Familia (Portuguese: Family Health Program; Brazil) |
| PSF | Point Spread Functions |
| PSF | Professional Service Firm |
| PSF | Phoneme Segmentation Fluency (standardized test; Dynamic Indicators of Basic Early Literacy Skills) |
| PsF | Progressive Segmented Frame (video) |
| PSF | Playstation Sound Format (file extension) |
| PSF | Pennsylvania Shakespeare Festival (est. 1992) |
| PSF | Phenolic Surface Film (plywood) |
| PSF | Presbyterian Student Fellowship |
| PSF | Performance Shaping Factor (nuclear power) |
| PSF | Proteus Syndrome Foundation |
| PSF | Peoples Students Federation (Pakistan) |
| PSF | Public Safety Factor (federal prison inmate security score) |
| PSF | Priority Solidarity Fund |
| PSF | Projet San Francisco |
| PSF | Pressure Sand Filter |
| PSF | Program Support Facility |
| PSF | Peak Scatter Factor (radiation) |
| PSF | Proof Setup File (Adobe Photoshop file extension) |
| PSF | Pusan Storage Facility |
| PSF | Pukhtun Students Federation |
| PSF | Pseudo-Skeptic-Fanatic |
| PSF | Planetary Super Freighter (gaming) |
| PSF | Practicing Spoken French |
| PSF | Pendejos Sin Fronteras (foreign supporters of Hugo Chavez) |
| PSF | Printing Support Facility |
| PSF | Pilot Symbol Filter |
| PSF | Procurement Status File |
| PSF | Pressure Single Filer |
| PSF | Probabilistic Spectrum Fitting |
| PSF | Pay Service File |
| PSF | Pencak Silat of France |
| PSF | Personal Security File (Australia) |
| PSF | Periodic Symmetric Function (computational mathematics) |
| PSF | Perennialized Stream Flow |
| PSF | Power Steering Fluid |
| PSF | Philippine Special Force (video gaming group) |
| PSF | Protein Structure and Function |
| PSF | Permanent School Fund |
| PSF | Pearson Scott Foresman (elementary educational publisher) |
| PsF | Polysulfone (polymer) |
| PSF | pound per square foot |
| PSF | Point Spread Function |
| PSF | Pittsfield, Massachusetts |
| PSF | Per Square Foot |
| PSF | Polyester Staple Fiber (textiles) |
| PSF | Pounds per Square Foot |
| PSF | Power Systems Facility (LERC Facility) |
| PSF | Presidio of San Francisco |
| PSF | Print Services Facility |
| PSF | Public School Finance (various locations) |
| PSF | Phelps-Stokes Fund (Washington, DC) |
| PSF | Photonic Switch Fabric |
| PSF | Peace Support Force |
| PSF | Postscript Fonts (Adobe) |
| PSF | Patrimoine sans Frontieres (French: Heritage without Borders) |
| PSF | Pharmaciens Sans Frontieres |
| PSF | Public Service Fellowship (various schools) |
| PSF | Posterior Spinal Fusion |
| PSF | Passenger Service Fee (India) |
| PSF | Product Service Facility |
| PSF | Private Sector Foundation (Uganda) |
| PSF | Project and Structured Finance (various organizations) |
| PSF | Partnership for Strong Families |
| PSF | Point Spread Function (optics) |
| PSF | Pakistan Science Foundation |
| PSF | Poisson Summation Formula |