| Acronym | Definition |
|---|
| PFC | Private First Class |
| PFC | Prefrontal Cortex |
| PFC | Press For Change (UK transgender lobby group) |
| PFC | Portsmouth Football Club |
| PFC | Passenger Facility Charge (airlines) |
| PFC | Policy Feature Card (Cisco Systems) |
| PFC | Partnership for Children |
| PFC | Porous Friction Course (pavement type) |
| PFC | Production Flexibility Contract |
| PFC | Plaque-Forming Cells |
| PFC | Personal Filing Cabinet |
| PFC | Powerbuilder Foundation Class |
| PFC | Power Finance Corporation Ltd (India) |
| PFC | Persistent Fetal Circulation |
| PFC | Priority Flow Control |
| PFC | Perfluorinated Compound |
| PFC | Pre Foreclosure (real estate) |
| PFC | Press-Fit Condylar (knee replacement design by DePuy Orthopaedics Inc) |
| PFC | Parallel Flange Channel (construction industry) |
| PFC | Pioneers for Christ |
| PFC | Patrolman First Class (law enforcement rank) |
| PFC | Perfluorinated Carbons |
| PFC | Partnership for Caring, Inc |
| PFC | Peak Friction Coefficient |
| PFC | Per-Fluoro Compound |
| PFC | Philatelic Foundation Certificate |
| PFC | Perfluorated Carbon |
| PFC | Partners For Community |
| PFC | Perfect Fried Chicken (London restaurant) |
| PFC | Pig's Favorite Customer (Piggly Wiggly grocery stores' customer rewards program) |
| PFC | Partizan Football Club (Belgrade, Serbia) |
| PFC | Parallel Flow Condenser |
| PFC | Psykiatriskt Forskningscentrum (Sweden) |
| PFC | Preliminary Flight Certification |
| PFC | Plastic Forming Company |
| PFC | Professional Fraternity Council |
| PFC | Programmable Fieldbus Coupler |
| PFC | Pleated-Foil Covered |
| PFC | Personal/Portable Fuel Cell |
| PFC | Plague Forming Cells |
| PFC | Pulse-Flow Coulometry |
| PFC | Paid From Credits |
| PFC | Premium Fund Check (insurance) |
| PFC | Piezo-Fiber Composite(s) |
| PFC | Plain Freaking Crazy (polite form) |
| PFC | Protection Factor Category |
| PFC | Professional Floor Cleaner |
| PFC | Proliferative Fibrocystic Changes (breast tumors) |
| PFC | Precision Fabrication and Cleaning |
| PFC | Prefix-Free Code |
| PFC | Power Factor Correction/Correcting |
| PFC | Professional Foster Care |
| PFC | Princeton Fire Company |