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The pneumococcal polysaccharide vaccine protects against 23 types of pneumococcal bacteria. The pneumococcal polysaccharide vaccine (PPV), which is available for use in adults, consists of purified capsular polysaccharide from the 23 serotypes of pneumococcus, which account for approximately 85%-90% of cases of invasive pneumococcal disease. Immune parameters included secretory IgA (sIgA) in saliva, cell-mediated immunity (CMI), determined using the CMI multitest where test antigens are applied to the skin, and antibody responses to both rabies and pneumococcal polysaccharide vaccines. |
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