| Acronym | Definition |
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| PDE | Pennsylvania Department of Education | | PDE | Plug-In Development Environment | | PDE | Partial Differential Equation | | PDE | Phosphodiesterases | | PDE | Pulse Detonation Engine | | PDE | Product Data Exchange | | PDE | Personal Digital Entertainment | | PDE | Plataforma en Defensa de l'Ebre (Catalan: Platform for the Defence of the River Ebre) | | PDE | Paramount Digital Entertainment | | PDE | Position Determining Entity | | PDE | Present-Day English | | PDE | Prescription Drug Event | | PDE | Plataforma en Defensa del Ebro (Spanish: Platform for the Defence of the River Ebre) | | PDE | Photon Detection Efficiency | | PDE | Product Design Engineer | | PDE | Primark Decision Economics | | PDE | Pyridoxine-Dependent Epilepsy | | PDE | Portable Electronic Device | | PDE | Production Estimate | | PDE | Primary Designated Engineer | | PDE | Project Development Engineer | | PDE | Process Development Engineer | | PDE | Potential Daily Exposure | | PDE | Philadelphia Drug Exchange | | PDE | Projected Operational Environment | | PDE | Pre-Emphasis/De-Emphasis | | PDE | Propagation Delay Estimation | | PDE | Preliminary Determination of Epicenter(s) (USGS) | | PDE | Paddle Drive Electronics | | PDE | Preliminary Data Element | | PDE | Project/Program Director, Electronics | | PDE | Permission Display Engine | | PDE | Predictive Density Estimation | | PDE | Planning, Decision, and Execution |
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