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| Acronym | Definition |
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| PFE | Pfizer, Inc. (stock symbol) | | PFE | Potential Future Exposure (credit risk) | | PFE | Partial Fraction Expansion | | PFE | Premier Field Engineer (Microsoft) | | PFE | Packet Forwarding Engine | | PFE | Packet Forwarding Engine (Siber-Core Technologies) | | PFE | Pressurized Fluid Extraction | | PFE | Portable Fire Extinguisher | | PFE | Power Feed Equipment (sea cabling) | | PFE | Pacific Fruit Express Company | | PFE | Promotion Fitness Examination | | PFE | Pelvic Floor Exercise | | PFE | Page Fault Error | | PFE | Please Find Enclosed | | PFE | Proyecto Filosofía en Español (Spain) | | PFE | Pulmonary Fat Embolism | | PFE | Priests for Equality | | PFE | Physical Foundations of Engineering | | PFE | Purchaser Furnished Equipment | | PFE | Pedal Feel Emulator | | PFE | Professional Flight Engineer | | PFE | Post Fire Evaluation | | PFE | Pilot Flight Equipment | | PFE | Proficiency Flight Evaluation (US Army) | | PFE | Piani Funzionali di Emergenza | | PFE | Personal Fitness Evaluation | | PFE | Professional Field Engineer | | PFE | Pulse-Field Electrophoresis | | PFE | Packet Filtering Engine | | PFE | Planning for Employment (North York, Canada) | | PFE | Percent Forecast Error (finance) | | PFE | Partnership for Education | | PFE | Patient and Family Education (various organizations) |
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