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PGC |
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At gastrulation, the primordial germ cells (PGCs) are newly formed and exhibit methylation similar to the surrounding somatic cells (Hajkova et al. The scientists have also found that in normal mice, SDF-1 is produced in a ridge of gonadal cells and that mouse primordial germ cells sport a protein called CXCR4 that detects the chemokine. To date, Origen has published research in Nature demonstrating its ability to make modifications to the chicken genome and create transgenic chickens by introducing the desired new genetic elements into primordial germ cells, the precursor cells to sperm and eggs. |
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