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? References in periodicals archive |
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4539, a novel small molecule inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) in development for the treatment of tissue damage, improved renal function and achieved today announced that the Company has received a Phase II Small Business Innovation Research (SBIR) grant from the National Heart, Lung, and Blood Institute (NHLBI), part of National Institutes of Health (NIH), which provides continued support for the development of FibroGen hypoxia-inducible factor prolyl hydroxylase ( 4539, its novel small molecule inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) in development for the treatment of ischemic disease, was neuroprotective and significantly reduced brain tissue damage in a preclinical model of permanent ischemic stroke. |
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