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Many of these effects may be attributed to the capability of these metals to inhibit protein tyrosine phosphatase activity (Samet et al. Ileana Cuevas from the Daniel Sanchez Laboratory (University of General San Martin, San Martin, Argentina) reported the presence of a farnesylated protein tyrosine phosphatase in T. Investigators say they have identified STAT3 {signal transducer and activator of transcription 3}, as a target regulated by PTPRT {Receptor Protein tyrosine phosphatase T}, which was previously identified to be mutated in colon, lung and stomach cancer patients. |
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