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Going forward, Daiichi Pharmaceutical will proceed with research on the newly-discovered protein-protein interactions with a view to leveraging them in the development of products. The Platform, called ProCode, can be configured for monoclonal antibody selection, affinity maturation and library generation, for improving solubility and bioactivity of biopharmaceuticals, as well as identification and characterization of protein-protein interactions and discovery of protein drugs. Through collaborative research on a variety of intramural projects, NCT researchers are employing MS to shed light on how protein expression and protein-protein interactions are affected by exposure to different environmental toxicants, and are making progress toward development of protein biomarkers that can be used for diagnosing exposure. |
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