In addition, resveratrol has been shown to deacetylate p53 by activating the SIRT1 pathway, reducing cisplatin-induced injury to proximal tubular epithelial cells
in mice , and doxorubicin-induced myocardial apoptosis .
Erythrophagocytosis occurs primarily in cells of the spleen and liver, but proximal tubular epithelial cells in the kidney also have this capability.
In this study the researchers hypothesized that lead exposure increases the number of PS-tagged erythrocytes, which are then consumed by the proximal tubular epithelial cells in the kidney.
PCR showed the mRNA expression of ALX could be detected in both mice renal tissue and human proximal tubular epithelial cells
MDCK and LLC-PK1 (Porcine Kidney Proximal Tubular epithelial cell line, were exposed to oxalate (Ox) at a concentration of 300 [micro]mol and calcium oxalate monohydrate (COM) crystals at a concentration of 133 [micro]g/[cm.
Abbreviations: KE, Khella extract; Ox, Oxalate; COM, Calcium oxalate monohydrate; CaOx, Calcium oxalate; MDCK, Madin-Canine Kidney collecting duct tubular epithelium cell line; LLC-PK1, Porcine Kidney Proximal Tubular epithelial cell line; LDH, Lactate dehydrogenase
In our study, KIM-1 expression was assessed in proximal tubular epithelial cells
from several groups representing patients with varying degrees of renal damage.
The aim of this study was to investigate the therapeutic effect of loganin in the streptozotocin (STZ)-induced DN model, to elucidate the potential mechanism, we focused on CTGF expression in blood, urine and kidney tissue of DN rats, CTGF expression was induced by high glucose (HG) in human renal proximal tubular epithelial cells (HK-2), and whether ERIC signaling pathway was involved.
Human renal proximal tubular epithelial cells (HK-2) were purchased from the Chinese typical culture example conservation centre (Wuhan, P.
Human proximal tubular epithelial cells
[HK-2; ATCC (American Type Culture Collection), Manassas, VA, USA] were maintained in keratinocyte serum-free media supplemented with recombinant epidermal growth factor, bovine pituitary extract (BPE), and 1% penicillin/streptomycin at 37[degrees]C under a 5% C[O.
Cystatin-C is produced by all nucleated cells and is freely filtered and absorbed by the megalin receptor in proximal tubular epithelial cells
(PTECs), where it is subsequently degraded.
Transthyretin and cystatin C are catabolized in proximal tubular epithelial cells
and the proteins are not useful as markers for renal cell carcinomas.