| Acronym | Definition |
|---|
| PLE | Palestine |
| PLE | Plato Learning Environment |
| PLE | Personal Learning Environment |
| PLE | Personal Learning Edition |
| PLE | Pleasurable |
| PLE | Plexmar Resources Inc. |
| PLE | Photoluminescence Excitation |
| PLE | Protein-Losing Enteropathy |
| PLE | Polymorphic Light Eruption |
| PLE | Product Line Engineering |
| PLE | Português Língua Estrangeira (Portugese) |
| PLE | Plethora Solutions (UK) |
| PLE | Public Legal Education (Canada) |
| PLE | Primary Leaving Examination (Uganda National Examinations Council; education) |
| PLE | Pressurised Liquid Extraction |
| PLE | Pymatuning Laboratory of Ecology (Pennsylvania) |
| PLE | Programmable Logic Element |
| PLE | Polypodium Leucotomos Extract |
| PLE | Peak Luminance Enhancement (NEC) |
| PLE | Power Line Engineering PCL (Thailand) |
| PLE | Perinatal Lethality |
| PLE | Programming Language Exploration |
| PLE | Page Life Expectancy |
| PLE | Phase-Locked Epitaxy |
| PLE | Primary Longman Express |
| PLE | Paiela Airport (Papua New Guinea) |
| PLE | Pioneer Living Experience |
| PLE | Pleasant Lea Elementary (Missouri) |
| PLE | Probable Limits of Error |
| PLE | Prudent Limit of Endurance |
| PLE | Product Line Executive |
| PLE | Professional Learning Exchange |
| PLE | Panel of Legal Experts |
| PLE | Pittsburgh and Lake Erie Railroad Company |
| PLE | Planeringsenhet (Swedish) |
| PLE | Planned Limit Endurance |
| PLE | PacketLink Environment |
| PLE | Participatory Learning Exercise |
| PLE | Papeterie les Entreprises (French: Stationery Enterprises; Canada) |
| PLE | Preliminary Logistic Evaluation |
| PLE | Port Liaison Element (diplomatic clearance requests for Navy ships visiting port.) |