73), se encontro que ambas estrategias utilizadas para disminuir el IMC ocasionan cambios en la excrecion de las proteinas albumina, transferrina, la proteina vesicular asociada a membrana 3 (VAMP3) y la RBP4
, las cuales fueron evaluadas en la orina.
IR was found to be accompanied by down-regulation of the insulin responsive glucose transporter-4 (GLUT4), which might be a signal for RBP4
secretion from adipocytes and development of systemic IR (8).
Additional work revealed parallel results in human blood samples: obese, insulin-resistant individuals had high RBP4
levels and lean, insulin-sensitive people had low RBP4
Considerando os niveis elevados de RBP4
em individuos ateroscleroticos, essa proteina pode constituir um bom biomarcador.
2012) Valproic Acid Downregulates RBP4
and Elicits Hypervitaminosis A-Teratogenesis-A Kinetic Analysis on Retinol/Retinoic Acid Homeostatic System.
The serum adiponectin and RBP4
were quantified by an enzyme-linked immunosorbent assay (AdipoGen, Seoul, Korea) using a standard curve constructed with a dilution series of a provided human RBP4
Se estudiaron genes candidatos para tamano de la camada en 300 hembras porcinas Yorkshire-Landrace; ESR, PRLR, RBP4
Cast F Cast R LEPR F LEPR R HTFA F P1 HTFA R P1 HTFA F P2 HTFA R p2 MC4R-F MC4R-R CCKAR-F CCKAR-R IGF2-F IGF2-R PRKAG3 F PRKAG3 R ESR A1 ESR B1 ESR R1 PRLR3 F PRLR4 F LIF F LIF R RBP4
R MYOG F MYOG R
Plasma concentrations of RBP4
(Immundiagnostik AG, Bensheim, Germany), leptin, adiponectin and glucagon (all from R&D Systems, Minneapolis, USA), and insulin (Mercodia, Uppsala, Sweden) were measured with specific enzyme-linked immunosorbent assays with the use of an automated analysis system (Triturus, Grifols SA, Barcelona, Spain) according to the manufacturer's instructions.
is a newly discovered fat derived adipokine that specifically binds to retinol  and transthyretin .
Scientists believe that a protein called RBP4
plays a crucial role in regulating insulin resistance when testosterone is impaired.
C3G significantly upregulated the glucose transporter 4 (Glut4) and downregulated RBP4
in the white adipose tissue, which is accompanied by downregulation of the inflammatory adipocytokines (monocyte chemoattractant protein-1 and tumor necrosis factor-alpha) in the white adipose tissue of the C3G group.