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RDEB |
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Our data provide the first evidence that a selected population of marrow cells can connect the epidermis and dermis in a mouse model of the disease and offer a potentially valuable approach for treatment of human RDEB and other extracellular matrix disorders. RDEB is a devastating congenital skin disorder characterized by painful ulcers and widespread, permanent scarring resulting in the deformity of hands and feet. The finding came about because roughly two-thirds of children with a blistering skin disorder called recessive dystrophic epidermolysis bullosa, or RDEB -- caused by a mutation that leads to an altered or missing collagen VII protein -- develop a type of skin cancer called squamous cell carcinoma. |
RDEB |
RDDAC RDDB RDDC RDDCF RDDE RDDF RDDI RDDL RDDL RDDM RDDME RDDMI RDDO RDDP RDDR RDDS RDDST RDDT RDDT&E RDDV RDDX RDE RDE&Q RDEA RDEAB RDEB RDECRdeci Traminac RDECOM RDECS RDEE RDEI RDEIR RDEIS RDEL RDEM RDEP RDEP2 RDEQ RDES RDEU Rdev RDEZ RDF RDF RDF RDF Data Query Language Rdf natural language RDF Schema RDF Schema RDF Site Summary RDF Site Summary RDF Vocabulary Description Language RDF/Ethernet | |||||
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