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RDEB

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AcronymDefinition
RDEBRecessive Dystrophic Epidermolysis Bullosa


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The finding came about because roughly two-thirds of children with a blistering skin disorder called recessive dystrophic epidermolysis bullosa, or RDEB -- caused by a mutation that leads to an altered or missing collagen VII protein -- develop a type of skin cancer called squamous cell carcinoma.
When children with RDEB encounter friction or trauma, the outer layer of skin simply peels away -- even from such friction as a parent picking up the child.
As a result, many RDEB patients require surgeries to allow greater use of their extremities resulting in a need for replacement skin.
 
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