| Acronym | Definition |
|---|
| RSC | Royal Society of Chemistry (UK) |
| RSC | Royal Shakespeare Company |
| RSC | Responsabilidad Social Corporativa (Spanish: corporate social responsibility) |
| RSC | Royal Society of Canada (La Societé Royale du Canada) |
| RSC | Roll Stability Control (Volvo) |
| RSC | Republican Study Committee |
| RSC | Reduced Shakespeare Company (comedy troupe) |
| RSC | Remote System Control |
| RSC | Radiation Safety Committee |
| RSC | Rehabilitation Services Commission |
| RSC | Remote Switching Center |
| RSC | Radio Systems Corporation (Knoxville, TN) |
| RSC | Runescape Community |
| RSC | Runescape Classic (gaming) |
| RSC | Regional Support Center |
| RSC | Regional Service Center |
| RSC | Rock Steady Crew (hip hop) |
| RSC | Regional Support Command |
| RSC | Regular Slotted Container |
| RSC | Richard Stockton College (New Jersey) |
| RSC | Rockwell Science Center |
| RSC | Reusable Software Component |
| RSC | Research Scholar |
| RSC | Recursive Systematic Convolutional (coding scheme) |
| RSC | Root Server Confederation |
| RSC | Russell Sage College (Troy, New York) |
| RSC | Regional Student Conference |
| RSC | Referee Stopped Contest (amateur boxing) |
| RSC | RISC Single Chip (IBM) |
| RSC | Reset Circuit (ISDN message) |
| RSC | Reverse Skills Certificate |
| RSC | Revised Statutes of Canada |
| RSC | Radar Scan Converter |
| RSC | Rigid Steel Conduit |
| RSC | Religious Sisters of Charity (religious order) |
| RSC | Route Switch Controller (Cisco) |
| RSC | Rescue Sub Centre |
| RSC | rescue sub-center (US DoD) |
| RSC | Reserve Support Command |
| RSC | Readiness Support Center (USACE) |
| RSC | Rural Service Center |
| RSC | Remote Service Center |
| RSC | Recumbent Stone Circle |
| RSC | Risk Specific Concentration |
| RSC | Red Shoulder Custom (Gundam/Votoms) |
| RSC | Romulan Star Command |
| RSC | Record Status Code |
| RSC | Request Scope PICurrent |
| RSC | Rough Scad (FAO fish species code) |
| RSC | Rotational Slingshot Catapult |
| RSC | RDT&E Support Complex (USAF) |
| RSC | Radar Set Control |
| RSC | red station clock (US DoD) |
| RSC | Radar Set Console |
| RSC | Reconnaissance Strike Complex |
| RSC | Rocket Systems Corporation (Japan) |
| RSC | Rotherham Sailing Club (UK) |
| RSC | Reduced Slot Cycle |
| RSC | Readability of Source Code |
| RSC | Record Service Center |
| RSC | Rolled Steel Channel |
| RSC | Range Safety Command |
| RSC | Return Subjourney Check (airfare construction) |
| RSC | Regional Support Company |
| RSC | Regional Supply Council |
| RSC | Routing Setting Controller |
| RSC | Rumen-Stable Choline |
| RSC | Range Support Center (USACE) |
| RSC | Rectangular Slotted Container |
| RSC | Refractive Surgery Clinic |
| RSC | Reliability, Supportability, and Cost |
| RSC | Runway Surface Covering (amount of rain, ice, snow; USAF) |
| RSC | Repair Source Category |
| RSC | Rebate Service Center LLC |
| RSC | Radar System Control |
| RSC | Refueling Sequence Chart |
| RSC | Ralph Stone and Company, Inc (Los Angeles, CA) |