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RYR |
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Other previously known triggers of the ryanodine receptor, including caffeine, have negligible effects except at extremely high concentrations. In addition, PCBs can produce toxic effects by binding either to the aryl hydrocarbon receptor (Safe 1990) or the ryanodine receptor (Schantz et al. Linkage to the ryanodine receptor gene, the dihydropyridine membrane calcium channel, and the second-messenger inositol polyphosphate system has been found, but not consistently. |
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